Research digest
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Determining the “IMPACT” of therapeutics for depression requires an adaptive trial design
A large proportion of adolescents suffering from moderate-to-severe major depression respond to psychological and pharmacological therapy, and the range of effective treatment modalities is increasing. Now, Ian Goodyer and Paul Wilkinson have compiled a Practitioner Review that compares the various treatment options available and assesses their effectiveness for adolescents affected by major depressive episodes.
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The trajectories of depressive symptoms expressed in early childhood differ between boys and girls
A study by Diana Whalen and colleagues at Washington University has used latent class analysis (LCA) to identify and define the trajectories of latent classes of depressive symptoms in early childhood.
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Genetic factors influence the relationship between the home environment and onset of depressive symptom
Clinical depression is prevalent in adolescence, but how depression emerges and the nature of the early risk factors is unknown. Insight has now come from a study performed by researchers at King’s College London.
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Depression is highly prevalent but under-reported in children with ADHD
Researchers at Cardiff University have investigated whether the symptoms of depression observed in patients with attention-deficit/hyperactivity disorder (ADHD) differ from those reported in the general population.
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Accelerated cortical thinning correlates with early signs of depression
The brain undergoes structural changes as it develops over childhood, but whether abnormal structural changes are associated with emerging depressive symptoms in adolescence is unknown. Now, a longitudinal study that enrolled 205 participants aged 8-25 years without signs of depression has used magnetic resonance imaging (MRI) to monitor these brain changes over adolescence.
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Routine Outcome Measurement in CAMHS
This article is a summary of the paper published in CAMH – Waldron, S. M., Loades, M. E., & Rogers, L. (2018). Routine Outcome Monitoring in CAMHS: How Can We Enable Implementation in Practice?
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Promoting participation to improve mental health outcomes in children aged 11-13 years
This article is a summary of the paper published in CAMH – Tokolahi, E., Vandal, A. C., Kersten, P., Pearson, J., & Hocking, C. (2018). Cluster-randomised controlled trial of an occupational therapy intervention for children aged 11-13 years, designed to increase participation to prevent symptoms of mental illness.
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Eating disorders – Foreword from the Editor
Welcome to this edition of The Bridge which focuses on eating disorders.
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Persistent picky eating predicts pervasive developmental disorders in children
Picky eating — characterized by food refusal, unwillingness to try new foods or eating a limited variety of foods — affects 14-50% preschool children and is often considered by clinicians as a normal phase of child development.
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Targeting the neural task-control circuitry to enhance self-regulatory control in bulimia nervosa
Previous research has found that bulimia nervosa is associated with dysregulated self-regulatory control, as a result of anatomical and functional disturbances to the neural task-control circuitry in the brain.
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