Substance misuse

  • teenagers sitting, drinking beer from glass bottle and holding cigarette

    Neuroanatomical Variability and Early Substance Use Initiation: Insights from the ABCD Study

    Adolescence is a period of rapid brain development, making it a sensitive window for experiences that may shape long-term outcomes. A new study from the Adolescent Brain Cognitive Development (ABCD) project examined whether neuroanatomical variability is linked to early initiation of alcohol, nicotine, or cannabis. Drawing on baseline brain images taken before substance use began, the researchers found regionally specific differences in cortical thickness and surface area among early initiators. The findings highlight the complexity of adolescent neurodevelopment and point to the value of large-scale, longitudinal studies in clarifying how brain structure and behaviour unfold together.

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  • Do brain function abnormalities lead to substance use, or vice versa?

    New research has, for the first time, investigated the direction of links between brain function and substance use throughout adolescence. Jungmeen Kim-Spoon and colleagues studied 167 adolescents who were assessed annually for four years from 13-14 years old.

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  • Can population registry data predict which children with ADHD are at risk of later substance use disorders?

    The first study to examine the potential of machine learning in early prediction of later substance use disorders (SUDs) in youth with ADHD has been published in the Journal of Child Psychiatry and Psychology.

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  • July 2020 – The Bridge

    In this issue, we summarise recent studies on a wide range of topics – including sleep, sensory symptoms, emotional symptoms, disinhibition, alcohol misuse, complex PTSD symptoms, and self-harm – which reveal new insights helping us to better understand and address psychopathology in young people.

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  • Global development and injecting drug use in a new generation of adolescents

    People who inject drugs tend to begin doing so in adolescence, and countries that have larger numbers of adolescents who inject drugs may be at risk of emerging epidemics of blood borne viruses unless they take urgent action.

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  • January 2020 issue – The Bridge ADHD edition

    Special edition of The Bridge on ADHD, includes guidelines on service transition for young people, substance use, emotional impulsivity, emotion dysregulation, diagnosis and misdiagnosis.

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  • Gender-specific pathways mediate the risk of substance use in adolescents with ADHD

    Data suggest that children with attention-deficit/hyperactivity disorder (ADHD) are more likely to start smoking tobacco and/or marijuana earlier in childhood than unaffected children, and then escalate use during adolescence. Now, a study by researchers at the University of Minnesota has examined the mediating pathways underlying this association between childhood ADHD and later substance-abuse problems.

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  • Homelessness and its impact on children

    In the run up to Christmas, this article aims to outline previous research on the effects of homelessness and the potential solutions already outlined, as well as point towards future research and actions.

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  • Guest blog on sleep and mental health

    Sleep and Mental Health

    Dr Sally Hobson, Specialty Community Paediatrician, Evelina Children’s Secondary Community Sleep Clinic on the relationship between sleep and mental health.

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  • A cup half full or half empty? A reflection on 15 years working with Fetal Alcohol Spectrum Disorders (FASD) in the UK

    “It has been 15 years now that I have been working within the field of specialist diagnosis and behavioural management of individuals with FASD. At this point in my journey, as well as the journey of FASD diagnostic services in the UK, it felt like a good time to step sideways and reflect on how far we had come and where we still have yet to go.”

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