‘A network approach to the investigation of childhood irritability: probing frustration using social stimuli’
Paper from the JCPP
Self-regulation in early childhood develops within a social context. Variations in such development can be attributed to inter-individual behavioral differences, which can be captured both as facets of temperament and across a normal:abnormal dimensional spectrum. With increasing emphasis on irritability as a robust early-life transdiagnostic indicator of broad psychopathological risk, linkage to neural mechanisms is imperative. Currently, there is inconsistency in the identification of neural circuits that underlie irritability in children, especially in social contexts. This study aimed to address this gap by utilizing a functional magnetic resonance imaging (fMRI) paradigm to investigate pediatric anger/frustration using social stimuli.
Authors: Khalil I. Thompson, Clayton J. Schneider, Justin A. Lopez-Roque, Susan B. Perlman, Helmet T. Karim, Lauren S. Wakschlag
First published: 20 December 2023
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