‘Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry’
Open Access paper from the JCPP
Depression and anxiety are the most common mental health problems in young people. Currently, clinicians are advised to wait before initiating treatment for young people with these disorders as many spontaneously remit. However, others develop recurrent disorder but this subgroup cannot be identified at the outset. We examined whether psychiatric polygenic scores (PGS) could help inform stratification efforts to predict those at higher risk of recurrence.
Authors: Charlotte A. Dennison, Joanna Martin, Amy Shakeshaft, Lucy Riglin, Frances Rice, Cathryn M. Lewis, Michael C. O’Donovan, Anita Thapar
First published: 19 July 2023
https://doi.org/10.1111/jcpp.13862
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