The role of inflammation in the prospective associations between early childhood sleep problems and ADHD at 10 years: findings from a UK birth cohort study

Open Access paper from the JCPP

Background – Several underlying mechanisms potentially account for the link between sleep and attention deficit and hyperactivity disorder (ADHD), including inflammation. However, studies so far have been cross sectional. We investigate (a) the association between early childhood sleep and probable ADHD diagnosis in childhood and (b) whether childhood circulating inflammatory markers mediate these prospective associations.

Authors; Isabel Morales-Muñoz, Rachel Upthegrove, Kate Lawrence, Rasiah Thayakaran, Sandra Kooij, Alice M Gregory, Steven Marwaha

First published: 03 January 2023

doi.org/10.1111/jcpp.13755

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